Shape of proteins for living things : Molecules of COVID-19

Shape of proteins for living things : Molecule of COVID-19

Movies (YouTube) for Science Fiesta(5min) for mainly Spikes(8 min) for all the pages(14 min)

Narrations of the movies are Japanese, but English subtitles are available.

COVID-19 is an infectious disease caused by SARS corona virus 2 (SARS-CoV-2). Many researchers solve the three dimensional structures of corona virus protein and deposit them to PDB database in order to explore the mechanism of infection and develop effective therapies. Look into structures of various corona viruses, to learn the mechanism of infection, the immune system, and the mutant variants.

If you have any questions and comments, please ask via [PDBj contact us page].

The movie for Science Fiesta(5min) has been provided for Web Science Fiesta 2021.

We use the software Molmil to show 3D structure of molecules in web browsers. It can be used without any installation procedures.

A particle of corona virus

20 amino acids for proteins

Spike protein

Spike can close and open

Spike proteins and human ACE2 receptors

Antibodies, in response to vaccine, bind to spikes to prevent infection

Antibody cocktail

Spike of variant has a slightly different amino acids

RNA-denpendent RNA polymerase and remdesivir

3C-like protease and its inhibitors