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Antibody cocktail (PDB ID:6xdg, PDB ID:6vsb)

[日本語]

An antibody cocktail is a mixture of multiple antibodies to protect us from disease. This is a structure of spike proteins with two antibodies, "casirivimab"(green) and "imdevimab"(red). They inhibit the spikes to bind human receptors. These two antibodies bind to the different region of spike RBD domains. The combination of these two antibodies aims to decrease the virus escape mutants.

Spike proteins Antibodies Casirivimab Imdevimab
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Alpha variant N501Y P681H
Delta variant T19R G142D L452R T478K D614G P681R D950N